Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29139533 | 0.79 | KMT2A (0.42) | KMT2ACLK1POLBKMONOTUM | |
| SCHEMBL203715 | 0.77 | MCL1 (0.44) | KMT2ACLK1POLBKMOALDH1A1 | |
| SCHEMBL13106271 | 0.74 | POLB (0.46) | KMT2APOLBKMOLMNANR4A2 | |
| SCHEMBL11748058 | 0.71 | IDE (0.47) | KMT2APOLBALDH1A1ELANEMCL1 | |
| SCHEMBL11749925 | 0.70 | LMNA (0.42) | KMT2ACLK1ALDH1A1MCL1GAA | |
| SCHEMBL11747559 | 0.70 | KMT2A (0.42) | KMT2APOLBALDH1A1MCL1GAA | |
| SCHEMBL2733644 | 0.68 | MCL1 (0.41) | KMT2APOLBKMOALDH1A1CYP3A4 | |
| SCHEMBL19532532 | 0.68 | ELANE (0.40) | KMT2AKMOELANEKDM4EMAPT | |
| SCHEMBL8300318 | 0.67 | PDGFRA (0.46) | KMT2ACLK1KMOALDH1A1CYP3A4 | |
| SCHEMBL20820754 | 0.66 | KDM4C (0.38) | KMT2APOLBKMOCYP3A4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891484-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |