Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29139530 | 0.79 | KMT2A (0.49) | KMT2ACLK1LMNAKMOMCL1 | |
| SCHEMBL8300318 | 0.74 | PDGFRA (0.46) | KMT2ACLK1PDGFRACDK5TYRO3 | |
| SCHEMBL11748058 | 0.67 | IDE (0.47) | KMT2ALMNAMCL1ALDH1A1KDM4E | |
| SCHEMBL203715 | 0.67 | MCL1 (0.44) | KMT2ACLK1KMOMCL1ALDH1A1 | |
| SCHEMBL13106380 | 0.66 | POLB (0.39) | KMT2AKMOALDH1A1KDM4CPOLB | |
| SCHEMBL11747559 | 0.66 | KMT2A (0.42) | KMT2ALMNAMCL1ALDH1A1KDM4E | |
| SCHEMBL11749925 | 0.66 | LMNA (0.42) | KMT2ACLK1LMNAMCL1ALDH1A1 | |
| SCHEMBL28198349 | 0.65 | KDM4C (0.42) | KMT2AKMOALDH1A1CYP3A4KDM4E | |
| SCHEMBL28748691 | 0.64 | PPP1CA (0.45) | KMT2AKMOMCL1ALDH1A1CYP3A4 | |
| SCHEMBL205202 | 0.64 | HPGD (0.42) | KMT2ACLK1KMOMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891484-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |