Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23853811 | 0.80 | HTR1A (0.40) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL2563345 | 0.77 | HTR1A (0.38) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL31438527 | 0.76 | KDM4E (0.34) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL25190850 | 0.76 | KDM4E (0.34) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL31389417 | 0.75 | P2RX7 (0.38) | SLC6A2SLC6A4P2RX7 | |
| SCHEMBL29714391 | 0.74 | KDM4E (0.37) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL22778029 | 0.74 | KDM4E (0.37) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL3784551 | 0.73 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4 | |
| SCHEMBL18136226 | 0.73 | KAT2B (0.38) | RIPK1KDM4EMPIL3MBTL1HTR1A | |
| SCHEMBL29687939 | 0.73 | PARP1 (0.46) | KDM4EL3MBTL1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236415-B | Process for the preparation of aminopyrimidines and intermediates therefor | 赛特凯恩蒂克公司 | 2023-11-14 | — | — | CN | disclosed |