Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 13/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 9/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369916 | 0.85 | SSTR4 (0.38) | P2RX7SSTR4SSTR1SLC40A1HCRTR1 | |
| SCHEMBL31389612 | 0.78 | SSTR4 (0.34) | P2RX7SSTR4SSTR1SLC40A1HCRTR1 | |
| SCHEMBL31389421 | 0.76 | HTR1A (0.42) | SSTR4SSTR1SLC6A2SLC6A4 | |
| SCHEMBL23774666 | 0.76 | SLC40A1 (0.36) | P2RX7SSTR4SSTR1SLC40A1HCRTR1 | |
| SCHEMBL29139742 | 0.75 | RIPK1 (0.38) | P2RX7SLC6A2SLC6A4 | |
| SCHEMBL31389943 | 0.73 | PROKR1 (0.39) | P2RX7HCRTR1HCRTR2 | |
| SCHEMBL365001 | 0.73 | HTR1A (0.39) | SSTR4SSTR1SLC6A2SLC6A4 | |
| SCHEMBL30827599 | 0.71 | RXRA (0.41) | P2RX7SSTR4SSTR1SLC40A1HCRTR1 | |
| SCHEMBL27252060 | 0.71 | RXRA (0.41) | P2RX7SSTR4SSTR1SLC40A1HCRTR1 | |
| SCHEMBL21216421 | 0.69 | OPRL1 (0.39) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |