Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28142595 | 0.93 | FGFR1 (0.49) | FGFR1EGFRPI4KAPI4K2BPI4K2A | |
| Quinoline SCHEMBL27973568 | 0.89 | ALDH1A1 (0.45) | FGFR1EGFRPI4KAPI4K2BPI4K2A | |
| SCHEMBL4978113 | 0.84 | XDH (0.48) | FGFR1HTTXDHKDM4EALDH1A1 | |
| SCHEMBL30219641 | 0.82 | DHFR (0.49) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28301793 | 0.82 | DHFR (0.49) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11916214 | 0.80 | FGFR1 (0.47) | FGFR1EGFRPI4KAPI4K2BPI4K2A | |
| SCHEMBL28198782 | 0.80 | FGFR1 (0.47) | FGFR1HTTPDE10AALDH1A1SRC | |
| SCHEMBL17802582 | 0.79 | CFTR (0.54) | FGFR1KDM4EALDH1A1SMN1; SMN2ROCK1 | |
| SCHEMBL27745688 | 0.78 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBHTT | |
| SCHEMBL30069229 | 0.76 | FGFR1 (0.45) | FGFR1HTTPDE10AALDH1A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127063-B | Pyrimidine five-membered heterocyclic compounds and application thereof as mutant IDH2 inhibitor | 上海仕谱生物科技有限公司 | 2023-12-01 | — | — | CN | disclosed |