Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364155 | 0.86 | ALDH1A1 (0.46) | GPR119TGFBR1STSNR1H2 | |
| SCHEMBL28527952 | 0.84 | KMT2A (0.50) | GPR119STS | |
| SCHEMBL28831408 | 0.84 | NR1H2 (0.41) | GPR119TGFBR1STSNR1H2 | |
| SCHEMBL26631310 | 0.79 | MEN1 (0.46) | GPR119STSCYP11B2SCD5 | |
| SCHEMBL28909557 | 0.74 | TGFBR1 (0.47) | GPR119TGFBR1STS | |
| SCHEMBL28909554 | 0.74 | TGFBR1 (0.47) | GPR119TGFBR1STS | |
| SCHEMBL26738584 | 0.74 | KMT2A (0.47) | GPR119STSNR1H2 | |
| SCHEMBL28954399 | 0.74 | KAT6A (0.38) | TGFBR1STSNR1H2 | |
| SCHEMBL23902054 | 0.73 | MAPK1 (0.51) | GPR119TSHRALOX15ATMCYP11B2 | |
| SCHEMBL29609790 | 0.73 | MAPK1 (0.51) | GPR119TSHRALOX15ATMCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |