Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL12542065 | 1.00 | HSD17B10 (0.40) | HSD17B10CYP3A4CYP1A2CDK2HIF1A | |
| Ribose (Furanose) SCHEMBL1682946 | 1.00 | HSD17B10 (0.40) | HSD17B10CYP3A4CYP1A2CDK2HIF1A | |
| Ribose (Furanose) SCHEMBL7680729 | 0.84 | CYP3A4 (0.39) | HSD17B10CYP3A4CYP1A2CDK2HIF1A | |
| Adenine SCHEMBL7746165 | 0.84 | PI4KA (0.58) | CYP3A4CDK2HIF1AHTTLMNA | |
| Adenine SCHEMBL580228 | 0.84 | PI4KA (0.58) | CYP3A4CDK2HIF1AHTTLMNA | |
| Ribose (Furanose) SCHEMBL17824409 | 0.84 | ADK (0.40) | HSD17B10CYP3A4CYP1A2CDK2HIF1A | |
| Ribose (Furanose) SCHEMBL8605925 | 0.84 | ADK (0.40) | HSD17B10CYP3A4CYP1A2CDK2HIF1A | |
| Adenine SCHEMBL38386 | 0.84 | PI4KA (0.58) | CYP3A4CDK2HIF1AHTTLMNA | |
| Ribose (Furanose) SCHEMBL831005 | 0.84 | CYP3A4 (0.39) | HSD17B10CYP3A4CYP1A2CDK2HIF1A | |
| Adenine SCHEMBL7624128 | 0.84 | PI4KA (0.58) | CYP3A4CDK2HIF1AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301585-B1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD (IL) | 2015-01-07 | — | — | EP | disclosed |
| US-8835398-B2 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD. (IL) | 2014-09-16 | — | — | US | disclosed |
| US-20140155467-A1 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | VASCULAR BIOGENICS LTD. (IL) | 2014-06-05 | — | — | US | disclosed |
| US-20130295053-A1 | Methods of Producing Adenovirus Vectors and Viral Preparations Generated Thereby | VASCULAR BIOGENICS LTD (IL) | 2013-11-07 | — | — | US | disclosed |
| US-20130052165-A1 | Methods of Producing Adenovirus Vectors and Viral Preparations Generated Thereby | VASCULAR BIOGENICS LTD. (IL) | 2013-02-28 | — | — | US | disclosed |
| US-20130011367-A1 | Promoters Exhibiting Endothelial Cell Specificity and Methods of Using Same for Regulation of Angiogenesis | VASCULAR BIOGENICS, LTD. (IL) | 2013-01-10 | — | — | US | disclosed |
| EP-2523681-A1 | METHODS OF PRODUCING ADENOVIRUS VECTORS AND VIRAL PREPARATIONS GENERATED THEREBY | Vascular Biogenics Ltd. (IL) | 2012-11-21 | — | — | EP | disclosed |
| EP-2301586-B1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD (IL) | 2012-09-26 | — | — | EP | disclosed |
| US-8206743-B2 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD. (IL) | 2012-06-26 | — | — | US | disclosed |
| US-8071740-B2 | Isolated polynucleotide sequences; controlling neuvasculization ; cell growth factor | VASCULAR BIOGENICS LTD. (IL) | 2011-12-06 | — | — | US | disclosed |
| US-20100081193-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD. (IL) | 2010-04-01 | — | — | US | disclosed |
| EP-2152317-A2 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | Vascular Biogenics Ltd. (IL) | 2010-02-17 | — | — | EP | disclosed |
| EP-1988926-A2 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | Vascular Biogenics Ltd. (IL) | 2008-11-12 | — | — | EP | disclosed |
| WO-2008132729-A2 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | VASCULAR BIOGENICS LTD. (IL) | 2008-11-06 | — | — | WO | disclosed |
| US-20070286845-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD. (IL) | 2007-12-13 | — | — | US | disclosed |
| WO-2007096882-A2 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | VASCULAR BIOGENICS LTD. (IL) | 2007-08-30 | — | — | WO | disclosed |
| EP-1814897-A2 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | Vascular Biogenics Ltd. (IL) | 2007-08-08 | — | — | EP | disclosed |
| US-20060204478-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD. (IL) | 2006-09-14 | — | — | US | disclosed |
| WO-2006051545-A2 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS | VASCULAR BIOGENICS LTD. (IL) | 2006-05-18 | — | — | WO | disclosed |
| US-20050186179-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VASCULAR BIOGENICS LTD. (IL) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050186179-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VEGFA, CTCF, EDF1 | HSD17B10 2551/4885CYP3A4 4879/4885CYP1A2 4877/4885 |
| US-20060204478-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VEGFA, CTCF, EDF1 | HSD17B10 2551/4885CYP3A4 4879/4885CYP1A2 4877/4885 |
| US-20070286845-A1 | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis | VEGFA, CTCF, EDF1 | HSD17B10 2551/4885CYP3A4 4879/4885CYP1A2 4877/4885 |
| US-20130011367-A1 | Promoters Exhibiting Endothelial Cell Specificity and Methods of Using Same for Regulation of Angiogenesis | VEGFA, CTCF, EDF1 | HSD17B10 2551/4885CYP3A4 4879/4885CYP1A2 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.