Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30725587 | 0.86 | NR1H4 (0.49) | NR1H4ST14LTA4H | |
| Trifluoroacetic Acid SCHEMBL29142995 | 0.86 | NR1H4 (0.49) | NR1H4ST14LTA4H | |
| SCHEMBL24892365 | 0.72 | ST14 (0.55) | NR1H4ST14MEN1KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL29803776 | 0.70 | MLYCD (0.49) | NR1H4ST14MEN1KMT2AMAPT | |
| SCHEMBL7303178 | 0.70 | MEN1 (0.52) | ST14MEN1KMT2AMAPTNAMPT | |
| Hydrochloric Acid SCHEMBL9275424 | 0.69 | MAPT (0.51) | ST14MEN1KMT2AMAPTLMNA | |
| SCHEMBL29143007 | 0.69 | MAPT (0.45) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7303034 | 0.69 | NR1H4 (0.54) | NR1H4ST14MEN1KMT2AMAPT | |
| SCHEMBL24670339 | 0.68 | TRPV1 (0.50) | NR1H4ST14MEN1KMT2AMAPT | |
| SCHEMBL7943508 | 0.68 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447375-A | Guanidine compound, preparation method and application thereof | 中国医学科学院药物研究所 | 2024-01-26 | — | — | CN | disclosed |