Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | RARG | P13631 | 5/20 | 0.56 |
| ▸ | RARA | P10276 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17327789 | 0.88 | RARB (0.56) | RARBRARGRARASLC6A2SLC6A4 | |
| SCHEMBL8690673 | 0.86 | RARG (0.55) | RARBRARGRARAPDK2SLC6A2 | |
| SCHEMBL8688231 | 0.86 | RARG (0.55) | RARBRARGRARASLC6A2SLC6A4 | |
| SCHEMBL2914641 | 0.85 | RARB (0.68) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8693295 | 0.81 | RARG (0.50) | RARBRARGRARASLC6A2SLC6A4 | |
| SCHEMBL7932561 | 0.79 | MEN1 (0.64) | RARBRARGRARACA12CA1 | |
| SCHEMBL8688418 | 0.79 | RARA (0.47) | RARBRARGRARACYP3A4RXRA | |
| SCHEMBL8200161 | 0.78 | CA12 (0.71) | CA12CA1CA2CA7PDK2 | |
| SCHEMBL8661405 | 0.78 | RARB (0.54) | RARBRARGRARASLC6A4SLC6A3 | |
| SCHEMBL8690609 | 0.78 | RARA (0.54) | RARBRARGRARASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | claimed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | claimed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |