SCHEMBL29147405

SCHEMBL29147405

CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)NN

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 4/20 0.67
CTSK P43235 4/20 0.67
CA2 P00918 1/20 0.55
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 1/20 0.47
TSHR P16473 1/20 0.46
HPGD P15428 2/20 0.45
LMNA P02545 1/20 0.45
THRB P10828 1/20 0.45
KLK5 Q9Y337 1/20 0.45
EPHX2 P34913 1/20 0.44
HSD17B10 Q99714 1/20 0.44
BACE1 P56817 4/20 0.44
KLK7 P49862 1/20 0.42
REN P00797 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16495839 0.92 CTSS (0.59) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL16495837 0.92 CTSS (0.59) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL1918997 0.87 CTSS (0.69) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL21887355 0.87 CTSK (0.69) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL1105463 0.87 CTSK (0.69) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL3757938 0.87 CTSS (0.69) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL1918995 0.87 CTSS (0.69) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL15764474 0.86 CTSS (0.50) CTSSCTSKCA2
SCHEMBL18793329 0.85 CTSS (0.67) CTSSCTSKCA2KDM4EALDH1A1
SCHEMBL5730481 0.85 CTSS (0.67) CTSSCTSKCA2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447706-A Preparation method and application of methionine-tyrosine difunctional porous material 南京工业大学 2024-01-26 CN disclosed