Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.69 |
| ▸ | CTSK | P43235 | 4/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918995 | 1.00 | CTSS (0.69) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL3757938 | 1.00 | CTSS (0.69) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL21887355 | 0.88 | CTSK (0.69) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL1105463 | 0.88 | CTSK (0.69) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL18793329 | 0.87 | CTSS (0.67) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL29147405 | 0.87 | CTSS (0.67) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL10210703 | 0.87 | CTSS (0.67) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL5730481 | 0.87 | CTSS (0.67) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL1919361 | 0.86 | CTSS (0.57) | CTSSCTSKCA2KDM4EALDH1A1 | |
| SCHEMBL1919364 | 0.86 | CTSS (0.57) | CTSSCTSKCA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180340008-A1 | ANTIBIOTIC OLIGOPEPTIDE MIMETICS | BIOXINESS PHARMACEUTICALS INC (US) | 2018-11-29 | — | — | US | disclosed |
| US-20180298053-A1 | ANTIBIOTIC OLIGOPEPTIDES | BIOXINESS PHARMACEUTICALS INC (US) | 2018-10-18 | — | — | US | disclosed |
| US-20180282271-A1 | ANTIBIOTIC AMINO ACID MIMETICS | BIOXINESS PHARMACEUTICALS INC (US) | 2018-10-04 | — | — | US | disclosed |
| US-20170267632-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS INC (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170267632-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS INC (US) | 2017-09-21 | — | — | US | disclosed |
| US-9695119-B2 | Methionine analogs and methods of using same | BIOXINESS PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695119-B2 | Methionine analogs and methods of using same | BIOXINESS PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029369-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-20170029369-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2017-02-02 | — | — | US | disclosed |
| US-20150329481-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-20140142189-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8580859-B2 | Methionine analogs and methods of using same | BIOXINESS PHARMACEUTICALS, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580859-B2 | Methionine analogs and methods of using same | BIOXINESS PHARMACEUTICALS, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110196014-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICALS, INC. (CA) | 2011-08-11 | — | — | US | disclosed |
| EP-2326619-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | Bioxiness Pharmaceuticals, Inc. (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010014943-A2 | METHIONINE ANALOGS AND METHODS OF USING SAME | BIOXINESS PHARMACEUTICS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| US-6018020-A | VIRICIDES WHICH ARE PROTEASE INHIBITORS AGAINST HEPATITIS C AND HEPATITIS G | HOFFMAN-LA ROCHE INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0941233-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-15 | — | — | EP | disclosed |
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1998022496-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180340008-A1 | ANTIBIOTIC OLIGOPEPTIDE MIMETICS | DNPEP, NPEPPS, PEPD | CTSS 2182/4885CTSK 1331/4885CA2 4337/4885 |
| US-20180282271-A1 | ANTIBIOTIC AMINO ACID MIMETICS | DNPEP, MRPL21, PEPD | CTSS 2114/4885CTSK 1461/4885CA2 4697/4885 |
| US-20110196014-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | CTSS 1357/4885CTSK 2007/4885CA2 4831/4885 |
| US-20170267632-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | CTSS 1357/4885CTSK 2007/4885CA2 4831/4885 |
| US-20150329481-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | CTSS 1357/4885CTSK 2007/4885CA2 4831/4885 |
| US-20170029369-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | CTSS 1357/4885CTSK 2007/4885CA2 4831/4885 |
| US-20180298053-A1 | ANTIBIOTIC OLIGOPEPTIDES | DNPEP, NPEPPS, METAP1 | CTSS 2794/4885CTSK 1962/4885CA2 4747/4885 |
| US-20140142189-A1 | METHIONINE ANALOGS AND METHODS OF USING SAME | MTR, METAP1, AMD1 | CTSS 1357/4885CTSK 2007/4885CA2 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.