Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14738326 | 0.77 | MAP2K4 (0.33) | — | |
| SCHEMBL25335656 | 0.74 | PDPK1 (0.34) | — | |
| SCHEMBL14737657 | 0.74 | TRPA1 (0.35) | — | |
| SCHEMBL29490990 | 0.74 | PDPK1 (0.34) | — | |
| SCHEMBL578196 | 0.69 | TTK (0.52) | TTK | |
| SCHEMBL29921404 | 0.69 | TTK (0.52) | TTK | |
| SCHEMBL15568575 | 0.68 | MAP2K4 (0.43) | — | |
| SCHEMBL16584916 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL5952759 | 0.66 | PDPK1 (0.47) | TTK | |
| SCHEMBL15651137 | 0.66 | METAP2 (0.38) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964046-B | PLK4 inhibitors and uses thereof | 上海齐鲁制药研究中心有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116964046-A | PLK4 inhibitors and uses thereof | 上海齐鲁制药研究中心有限公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2022184049-A1 | PLK4 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2022-09-09 | — | — | WO | disclosed |