SCHEMBL2914893

SCHEMBL2914893

O=Nc1ccc(O)c2c(N=O)ccc(O)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.44
MAPT P10636 4/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
NPC1 O15118 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
RAB9A P51151 2/20 0.44
XBP1 P17861 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PIM1 P11309 1/20 0.43
THRB P10828 3/20 0.35
HPGD P15428 3/20 0.35
ALOX15 P16050 3/20 0.35
RECQL P46063 3/20 0.35
HSD17B10 Q99714 3/20 0.35
CASP1 P29466 2/20 0.35
APP P05067 1/20 0.35
TSHR P16473 1/20 0.35
SNCA P37840 1/20 0.35
POLB P06746 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12955990 0.97 TDP1 (0.42) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL589864 0.77 MAPT (0.41) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL3078639 0.76 MAPT (0.42) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL10918580 0.75 MEN1 (0.46) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL3087121 0.73 ALDH1A1 (0.39) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL20582829 0.72 RPS6KA3 (0.47) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL2602613 0.72 MAPT (0.40) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL1002641 0.70 KDM4E (0.39) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL1032621 0.70 IDO1 (0.59) TDP1MAPTKDM4EALDH1A1NPC1
SCHEMBL9296302 0.70 RPS6KA3 (0.42) TDP1MAPTKDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981719-B1 IMPROVEMENTS IN AND RELATING TO PRINTING INOVINK LTD (GB) 2010-09-01 EP claimed
US-20090212554-A1 PRINTING INOVINK LIMITED (GB) 2009-08-27 US claimed
EP-1981719-A1 IMPROVEMENTS IN AND RELATING TO PRINTING Inovink Limited (GB) 2008-10-22 EP claimed
WO-2007091094-A1 IMPROVEMENTS IN AND RELATING TO PRINTING INOVINK LIMITED (GB) 2007-08-16 WO claimed
US-11046104-B2 Security printing INOVINK LIMITED (GB) 2021-06-29 US disclosed
US-20200361228-A1 IMPROVEMENTS IN RELATION TO SECURITY PRINTING INOVINK LIMITED (GB) 2020-11-19 US disclosed
US-9358578-B2 Printing INOVINK LIMITED (GB) 2016-06-07 US disclosed
US-20140147576-A1 PRINTING INOVINK LIMITED (GB) 2014-05-29 US disclosed
EP-1981719-B1 IMPROVEMENTS IN AND RELATING TO PRINTING INOVINK LTD (GB) 2010-09-01 EP disclosed
US-20090212554-A1 PRINTING INOVINK LIMITED (GB) 2009-08-27 US disclosed
EP-1981719-A1 IMPROVEMENTS IN AND RELATING TO PRINTING Inovink Limited (GB) 2008-10-22 EP disclosed
WO-2007091094-A1 IMPROVEMENTS IN AND RELATING TO PRINTING INOVINK LIMITED (GB) 2007-08-16 WO disclosed