Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATIC | P31939 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914893 | 0.77 | TDP1 (0.44) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL3078639 | 0.75 | MAPT (0.42) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL12955990 | 0.75 | TDP1 (0.42) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL3087121 | 0.74 | ALDH1A1 (0.39) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL2602613 | 0.71 | MAPT (0.40) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL1032621 | 0.70 | IDO1 (0.59) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL1002641 | 0.70 | KDM4E (0.39) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL9296302 | 0.70 | RPS6KA3 (0.42) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL11783112 | 0.69 | CTSB (0.51) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| SCHEMBL22170101 | 0.66 | HSD17B10 (0.50) | MAPTTDP1ALDH1A1L3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12163968-B2 | Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers | BIO-RAD LABORATORIES, INC. (US) | 2024-12-10 | — | — | US | claimed |
| US-12163968-B2 | Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers | BIO-RAD LABORATORIES, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| EP-4208021-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | Bio-Rad Laboratories, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| CN-116097093-A | Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers | 生物辐射实验室股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022051443-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | BIO-RAD LABORATORIES, INC. (US) | 2022-03-10 | — | — | WO | disclosed |
| US-20220065878-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | BIO-RAD LABORATORIES, INC. | 2022-03-03 | — | — | US | disclosed |
| EP-2376908-B1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | BIO RAD LABORATORIES (US) | 2014-12-31 | — | — | EP | disclosed |
| CN-102341701-B | Mimetics of normal fresh platelets | BIO RAD LABORATORIES | 2014-07-09 | — | — | CN | disclosed |
| US-8114580-B2 | Simulation of normal fresh blood platelets for reference control | BIO-RAD LABORATORIES, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| EP-2376908-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | Bio-Rad Laboratories, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010083130-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | BIO-RAD LABORATORIES, INC. (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100178647-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | BIO-RAD LABORATORIES, INC. (US) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100178647-A1 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS | MPL, THPO, PFKP | MAPT 4876/4885TDP1 2078/4885KDM4E 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.