Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078639 | 0.78 | MAPT (0.42) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL3087121 | 0.77 | ALDH1A1 (0.39) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL2602613 | 0.74 | MAPT (0.40) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL9296302 | 0.73 | RPS6KA3 (0.42) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL2914893 | 0.70 | TDP1 (0.44) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL13123414 | 0.70 | MEP1B (0.34) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL589864 | 0.70 | MAPT (0.41) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL12955990 | 0.69 | TDP1 (0.42) | KDM4ENPC1ALDH1A1MAPTXBP1 | |
| SCHEMBL12580523 | 0.68 | ALB (0.47) | KDM4ENPC1MAPTL3MBTL1HSP90AA1 | |
| SCHEMBL13607302 | 0.68 | CA3 (0.44) | KDM4ENPC1ALDH1A1MAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298312-B1 | Fluorinated resorufin compounds and their application in detecting hydrogen peroxide | MOLECULAR PROBES INC (US) | 2018-09-26 | — | — | EP | disclosed |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation | 2017-02-09 | — | — | US | disclosed |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation | 2017-02-09 | — | — | US | disclosed |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation | 2017-02-09 | — | — | US | disclosed |
| US-9212385-B2 | Fluorinated resorufin compounds and their application | Life Technologies Corporation (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212385-B2 | Fluorinated resorufin compounds and their application | Life Technologies Corporation (US) | 2015-12-15 | — | — | US | disclosed |
| EP-1685117-B1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE | LIFE TECHNOLOGIES CORP (US) | 2015-01-07 | — | — | EP | disclosed |
| US-20140220612-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140220612-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140220612-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation (US) | 2014-08-07 | — | — | US | disclosed |
| US-7601851-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7432372-B2 | for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | INVITROGEN CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432372-B2 | for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | INVITROGEN CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432372-B2 | for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | INVITROGEN CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-20080113341-A1 | Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | INVITROGEN CORPORATION (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080113341-A1 | Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | INVITROGEN CORPORATION (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080113341-A1 | Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | INVITROGEN CORPORATION (US) | 2008-05-15 | — | — | US | disclosed |
| EP-1685117-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE | Molecular Probes Inc. (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005042504-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE | MOLECULAR PROBES, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20050096315-A1 | for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | Life Technologies Corporation | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | CYP2F1, CYP4F2, CYP4F3 | KDM4E 2370/4885NPC1 195/4885ALDH1A1 162/4885 |
| US-20050096315-A1 | for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays | GPX4, PRDX3, MPO | KDM4E 4139/4885NPC1 3248/4885ALDH1A1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.