Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | TP53 | P04637 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.66 |
| ▸ | RELA | Q04206 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002850 | 0.87 | MAPT (0.74) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL4650062 | 0.81 | MAPT (1.00) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL30626951 | 0.81 | FTO (0.72) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL31675778 | 0.81 | MAPT (1.00) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL29114186 | 0.81 | FTO (0.72) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.80 | MAPT (1.00) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| 6,4'-Dimethoxyflavone SCHEMBL29478471 | 0.80 | MAPT (1.00) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL29149150 | 0.80 | TNKS (0.50) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| 6-Methoxyflavone SCHEMBL312059 | 0.78 | ABCB1 (1.00) | MAPTTP53KDM4ECYP3A4ALDH1A1 | |
| 6-Methoxyflavone SCHEMBL30799564 | 0.78 | ABCB1 (1.00) | MAPTTP53KDM4ECYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447402-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-01-26 | — | — | CN | disclosed |