Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149150 | 0.84 | TNKS (0.50) | CSNK2A2CSNK2BCSNK2A1ESR2TNKS | |
| SCHEMBL30626959 | 0.81 | LCK (0.72) | CSNK2A2CSNK2BCSNK2A1LCKTNKS | |
| SCHEMBL29149144 | 0.74 | LCK (0.65) | CSNK2A2CSNK2BCSNK2A1LCKTNKS | |
| SCHEMBL312312 | 0.73 | MAPT (0.71) | CSNK2A2CSNK2BCSNK2A1FYNLCK | |
| SCHEMBL11564846 | 0.73 | AR (0.53) | TNKSKDM4ECYP3A4HPGDALDH1A1 | |
| SCHEMBL5477181 | 0.72 | PDE5A (0.38) | RAB9ANPC1 | |
| SCHEMBL31238531 | 0.72 | MAPT (0.72) | CSNK2A2CSNK2BCSNK2A1TNKSKDM4E | |
| SCHEMBL29149084 | 0.71 | MAPT (0.67) | CSNK2A2CSNK2BCSNK2A1TNKSKDM4E | |
| SCHEMBL30626952 | 0.70 | GABRP (0.61) | CSNK2A2CSNK2BCSNK2A1FYNESR2 | |
| SCHEMBL24046933 | 0.69 | ABCB1 (0.76) | KDM4ECYP3A4HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447402-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-01-26 | — | — | CN | disclosed |