Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924836 | 0.88 | GLP1R (0.43) | GPR119GLP1R | |
| SCHEMBL29149929 | 0.88 | TRPV3 (0.44) | GPR119TRPV3 | |
| SCHEMBL29556921 | 0.82 | GPR119 (0.56) | GPR119GLP1R | |
| SCHEMBL20266521 | 0.82 | GPR119 (0.56) | GPR119GLP1R | |
| SCHEMBL31192693 | 0.80 | GPR119 (0.51) | GPR119IRAK4TRPV3GLP1RJAK2 | |
| SCHEMBL31143232 | 0.80 | GLP1R (0.35) | GLP1R | |
| SCHEMBL31192683 | 0.79 | GPR119 (0.54) | GPR119IRAK4TRPV3 | |
| SCHEMBL22933035 | 0.77 | GPR119 (0.53) | GPR119TRPV3GLP1RJAK2JAK3 | |
| SCHEMBL22933040 | 0.77 | GPR119 (0.53) | GPR119TRPV3JAK2JAK3PTK2 | |
| SCHEMBL20346929 | 0.77 | GPR119 (0.58) | GPR119IRAK4JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |