Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149731 | 0.88 | GPR119 (0.51) | TRPV3GPR119 | |
| SCHEMBL29924828 | 0.88 | GLP1R (0.35) | — | |
| SCHEMBL24329751 | 0.81 | GLP1R (0.48) | TRPV3 | |
| SCHEMBL24330224 | 0.80 | TRPV3 (0.49) | TRPV3GPR119SMN1; SMN2MAPT | |
| SCHEMBL16434944 | 0.75 | HTT (0.51) | TRPV3GPR119THRBMAPTNPSR1 | |
| SCHEMBL24329325 | 0.75 | GPR119 (0.48) | TRPV3GPR119THRBMAPT | |
| SCHEMBL26930284 | 0.75 | GPR119 (0.56) | TRPV3USP30GPR119TP53THRB | |
| SCHEMBL21979953 | 0.75 | TRPV3 (0.54) | TRPV3USP30GPR119THRBSMN1; SMN2 | |
| SCHEMBL24329499 | 0.75 | GLP1R (0.45) | TRPV3GPR119TP53SMN1; SMN2 | |
| SCHEMBL29924836 | 0.75 | GLP1R (0.43) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |