Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933035 | 0.85 | GPR119 (0.53) | GPR119SMN1; SMN2TRPV3MAPTJAK2 | |
| SCHEMBL22933033 | 0.85 | KIF18A (0.54) | GPR119ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL22932905 | 0.81 | PKM (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL31192683 | 0.78 | GPR119 (0.54) | GPR119TRPV3 | |
| SCHEMBL29556921 | 0.78 | GPR119 (0.56) | GPR119 | |
| SCHEMBL20266521 | 0.78 | GPR119 (0.56) | GPR119 | |
| SCHEMBL22932959 | 0.78 | KDM4E (0.56) | GPR119TRPV3MAPTLMNAPOLB | |
| SCHEMBL20346929 | 0.78 | GPR119 (0.58) | GPR119MAPTTHRBJAK2JAK3 | |
| SCHEMBL29149731 | 0.77 | GPR119 (0.51) | GPR119TRPV3JAK2JAK3PTK2 | |
| SCHEMBL31192693 | 0.76 | GPR119 (0.51) | GPR119TRPV3JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018023-A1 | SMALL MOLECULE GLP-1 RECEPTOR MODULATOR | 济南泰达领创医药技术有限公司 | 2021-02-04 | — | — | WO | disclosed |