Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | C1S | P09871 | 2/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915012 | 0.85 | RAB9A (0.54) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL3268211 | 0.84 | CES2 (0.62) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL3876236 | 0.77 | CES2 (0.46) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL6296917 | 0.77 | KMT2A (0.56) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL28808144 | 0.76 | — | — | |
| SCHEMBL7647867 | 0.76 | CES2 (0.62) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL31438886 | 0.75 | RAB9A (0.47) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL27691133 | 0.75 | KMT2A (0.47) | RAB9ANPC1KMT2APKMHPGD | |
| SCHEMBL16856706 | 0.74 | KMT2A (0.53) | RAB9ANPC1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL27375514 | 0.74 | HPGDS (0.61) | RAB9ANPC1KMT2APKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080068-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES | Novo Nordisk A/S (DK) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999046237-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | disclosed |