Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057423 | 0.89 | GAA (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27976 | 0.78 | MGAM (0.61) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL12787244 | 0.77 | ALDH1A1 (0.43) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL18026348 | 0.75 | ALDH1A1 (0.47) | GAATSHRPOLBALDH1A1LMNA | |
| SCHEMBL15688315 | 0.75 | MGAM (0.58) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL6933557 | 0.73 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3181863 | 0.73 | ALDH1A1 (0.43) | GAATSHRPOLBALDH1A1LMNA | |
| SCHEMBL8248295 | 0.72 | RECQL (0.45) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7821951 | 0.70 | TSHR (0.46) | GAATSHRPOLBALDH1A1LMNA | |
| SCHEMBL1014529 | 0.70 | MGAM (0.46) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| EP-2223909-A1 | Process for preparing pentanoic diacid derivatives | Ratiopharm GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2223909-A1 | Process for preparing pentanoic diacid derivatives | Ratiopharm GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2181089-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | Ratiopharm GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009027081-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009027081-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |
| US-6657069-B2 | Reacting 6-aminocarbonylmethyl-4H-2,3- dioxin-4-one compound with alcohol or water to produce 3-oxopentanedicarboxylic acid amide esters; decyclization | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-02 | — | — | US | disclosed |
| US-20030130519-A1 | Amido compounds and process for producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. | 2003-07-10 | — | — | US | disclosed |
| US-6548674-B2 | 6-aminocarbonylmethyl-4H-1,3-dioxin-4-ones made by reacting a 6-halomethyl-4H-1,3-dioxin-4-ones with primary or secondary amine and carbon monoxide; intermediate to 3-oxopentanedicarboxylic acid amides for drugs, polyamides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20010023297-A1 | Amido compounds and process for producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-09-20 | — | — | US | disclosed |
| EP-1132386-A1 | Amido compounds and process for producing the same | Daicel Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130519-A1 | Amido compounds and process for producing the same | PAM, HAAO, DAO | MGAM 1253/4885GAA 3393/4885SI 1183/4885 |
| US-20010023297-A1 | Amido compounds and process for producing the same | PAM, HAAO, DAO | MGAM 1253/4885GAA 3393/4885SI 1183/4885 |
| US-20110065920-A1 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | HMGCR, DPYD, FDPS | MGAM 1973/4885GAA 744/4885SI 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.