Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22083926 | 0.87 | KMT2A (0.33) | USP2 | |
| SCHEMBL1358391 | 0.86 | — | — | |
| SCHEMBL22083530 | 0.85 | — | — | |
| SCHEMBL22083923 | 0.85 | — | — | |
| SCHEMBL22083456 | 0.85 | — | — | |
| SCHEMBL13415355 | 0.85 | SMN1; SMN2 (0.35) | HTT | |
| Topramezone SCHEMBL29566850 | 0.84 | — | — | |
| Topramezone SCHEMBL116121 | 0.84 | — | — | |
| SCHEMBL4700811 | 0.83 | ALKBH1 (0.31) | HTT | |
| SCHEMBL29152845 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486870-A | Topramezone derivative and application thereof | 山东德浩化学有限公司 | 2024-02-02 | — | — | CN | claimed |
| US-12550899-B2 | Topramezone derivative and use thereof | SHANDONG DEHAO CHEMICAL CO., LTD. (CN) | 2026-02-17 | — | — | US | disclosed |
| US-20250302044-A1 | TOPRAMEZONE DERIVATIVE AND USE THEREOF | SHANDONG DEHAO CHEMICAL CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| CN-117486870-B | Topramezone derivative and application thereof | 山东德浩化学有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117486870-A | Topramezone derivative and application thereof | 山东德浩化学有限公司 | 2024-02-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12550899-B2 | Topramezone derivative and use thereof | SYMPK, EML4, TET1 | ELANE 2586/4885USP2 3760/4885ALOX15 4287/4885 |
| US-20250302044-A1 | TOPRAMEZONE DERIVATIVE AND USE THEREOF | TPH1, TET1, KDM5A | ELANE 3506/4885USP2 3412/4885ALOX15 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.