SCHEMBL29153993

SCHEMBL29153993

COc1ccc(OP(=O)(Oc2ccc(OC)cc2)O[Se](=O)(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
CA1 P00915 6/20 0.42
CA2 P00918 6/20 0.42
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
HPGD P15428 1/20 0.42
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
PLK1 P53350 1/20 0.40
ACP3 P15309 1/20 0.40
LMNA P02545 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
PARP1 P09874 1/20 0.38
PARP10 Q53GL7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622317 0.81 CYP3A4 (0.65) CYP3A4TSHRCA1CA2CA12
SCHEMBL3084512 0.81 CYP3A4 (0.65) CYP3A4TSHRCA1CA2CA12
SCHEMBL29153987 0.75 GPR84 (0.53) CA1CA2CA9HTTNPC1
SCHEMBL28464795 0.74 PKM (0.62) CYP3A4TSHRCA1CA2CA12
SCHEMBL4277318 0.74 CYP3A4 (0.50) CYP3A4TSHRCA1CA2CA12
SCHEMBL22585040 0.74 CYP3A4 (0.83) CYP3A4TSHRCA1CA2CA12
SCHEMBL9621858 0.74 CYP3A4 (0.50) CYP3A4TSHRCA1CA2CA12
Nitrogen SCHEMBL28055470 0.74 CYP3A4 (0.50) CYP3A4TSHRCA1CA2CA12
SCHEMBL3246349 0.73 CES2 (0.53) CA1CA2CA12CA7CA9
SCHEMBL3219196 0.73 SRC (0.60) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805430-B Preparation method of selenophosphide and thiophosphoride 烟台大学 2024-02-13 CN disclosed