Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254957 | 0.84 | MAPT (0.56) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| Bromide SCHEMBL27219438 | 0.81 | EPHX2 (0.34) | EPHX2MAPT | |
| SCHEMBL10094219 | 0.77 | MAPT (0.47) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| SCHEMBL28780452 | 0.76 | EPHX2 (0.50) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| Water SCHEMBL27611031 | 0.75 | MAPT (0.45) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| Bromide SCHEMBL27876451 | 0.75 | SLC6A2 (0.37) | MAPTKDM4EKMT2ASLC6A4MEN1 | |
| SCHEMBL13863723 | 0.74 | MAPT (0.48) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| SCHEMBL255560 | 0.74 | GPR3 (0.52) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| Bromide SCHEMBL28835121 | 0.73 | MAPT (0.44) | EPHX2MAPTGPR3L3MBTL1KDM4E | |
| Bromide SCHEMBL28042447 | 0.73 | GPR3 (0.46) | GPR3KIF11PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561245-A | Azole compounds for controlling invertebrate pests | FMC公司 | 2024-02-13 | — | — | CN | disclosed |