SCHEMBL29155264

SCHEMBL29155264

C#Cc1cnc(OC(N)=O)nc1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.40
EGLN1 Q9GZT9 1/20 0.33
AURKA O14965 1/20 0.32
RPS6KB1 P23443 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13341591 0.81 ALDH1A1 (0.44) PARP1MEN1KMT2A
SCHEMBL27961002 0.77 PARP1 (0.40) PARP1EGLN1MEN1KMT2A
SCHEMBL28960220 0.75 MEN1 (0.35) MEN1KMT2A
SCHEMBL29178893 0.75 GABRA1 (0.33)
SCHEMBL29154131 0.75
SCHEMBL29178970 0.74 MEN1 (0.34) MEN1KMT2A
SCHEMBL19066140 0.74 KDM4E (0.36) MEN1KMT2A
SCHEMBL782969 0.73 MEN1 (0.37) MEN1KMT2A
SCHEMBL9852789 0.71 PARP10 (0.39) PARP1MEN1KMT2A
SCHEMBL6633239 0.70 MEN1 (0.43) PARP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466897-A Highly selective FGFR2 inhibitors 深圳福沃药业有限公司 2024-01-30 CN disclosed
CN-117343088-A 7- ((five membered heterocycle) methyl) -8-carboxylic acid-benzocyclobutane ester derivative and application thereof 福安药业集团重庆三禾兴医药科技有限公司 2024-01-05 CN disclosed