Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13960902 | 0.82 | MAPT (0.63) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL28629808 | 0.82 | MAPT (0.63) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL6998661 | 0.80 | MAPT (0.67) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL6998663 | 0.80 | MAPT (0.67) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL1673734 | 0.78 | MAPK1 (0.58) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL7701991 | 0.78 | ALDH1A1 (0.70) | MAPTHPGDALOX12CES2CES1 | |
| SCHEMBL3265780 | 0.77 | MAPT (0.53) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL7678400 | 0.77 | MAPT (0.58) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL7678407 | 0.77 | MAPT (0.58) | CYP1A2MAPTHPGDALOX12CYP2C19 | |
| SCHEMBL23659067 | 0.76 | CES2 (0.54) | CYP1A2MAPTHPGDALOX12CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106401868-B | A kind of pedestal vertical axis angle variable wind generator system and its working method | 徐州工程学院 | 2019-04-05 | — | — | CN | claimed |
| US-10383831-B2 | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use | Temple University—Of the Commonwealth System of Higher Education (US) | 2019-08-20 | — | — | US | disclosed |
| CN-106401868-B | A kind of pedestal vertical axis angle variable wind generator system and its working method | 徐州工程学院 | 2019-04-05 | — | — | CN | disclosed |
| CN-106242968-B | By α, method that β unsaturated carboxylic acids and ketone compounds directly synthesize the alpha-acyloxy ketone derivatives containing ethylenic unsaturation | 沅江华龙催化科技有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-106220496-B | By α, method that β unsaturated carboxylic acids and phenylpropyl alcohol ketone class compound directly synthesize the alpha-acyloxy ketone derivatives containing ethylenic unsaturation | 沅江华龙催化科技有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-106220495-B | The method that the alpha-acyloxy ketone derivatives containing ethylenic unsaturation are directly synthesized by α-reaction kinetic of ketone | 沅江华龙催化科技有限公司 | 2018-10-26 | — | — | CN | disclosed |
| US-20180243239-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2018-08-30 | — | — | US | disclosed |
| CN-106242968-A | The method being directly synthesized α acyloxy ketone derivatives containing ethylenic unsaturation by α, β unsaturated carboxylic acid and ketone compounds | 沅江华龙催化科技有限公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-106220495-A | The method being directly synthesized α acyloxy ketone derivatives containing ethylenic unsaturation by the α reaction kinetic of ketone | 沅江华龙催化科技有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-106220496-A | The method being directly synthesized α acyloxy ketone derivatives containing ethylenic unsaturation by α, β unsaturated carboxylic acid and propiophenone compounds | 沅江华龙催化科技有限公司 | 2016-12-14 | — | — | CN | disclosed |
| US-20110065715-A1 | Nogo Receptor Binding Small Molecules to Promote Axonal Growth | YALE UNIVERSITY (US) | 2011-03-17 | — | — | US | disclosed |
| EP-2220499-A2 | NOGO RECEPTOR BINDING SMALL MOLECULES TO PROMOTE AXONAL GROWTH | Yale University (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009073141-A2 | NOGO RECEPTOR BINDING SMALL MOLECULES TO PROMOTE AXONAL GROWTH | STRITTMATTER STEPHEN M (US) | 2009-06-11 | — | — | WO | disclosed |
| EP-0508549-B1 | New triazolopyrimidine and pyrazolopyrimidine derivatives useful for treating cachexia | SANKYO CO (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0347252-B1 | METHOD OF TREATING CACHEXIA AND CERTAIN NEW COMPOUNDS FOR USE IN THIS METHOD | SANKYO COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0508549-A2 | New triazolopyrimidine and pyrazolopyrimidine derivatives useful for treating cachexia | SANKYO COMPANY LIMITED (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5086057-A | METHOD OF TREATING CACHEXIA AND CERTAIN NEW COMPOUNDS FOR USE IN THIS METHOD | SANKYO COMPANY LIMITED (JP) | 1992-02-04 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10383831-B2 | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use | CCNY, STS, ARSA | CYP1A2 606/4885MAPT 4501/4885HPGD 3416/4885 |
| US-20110065715-A1 | Nogo Receptor Binding Small Molecules to Promote Axonal Growth | NGFR, GAP43, BDNF | CYP1A2 3387/4885MAPT 333/4885HPGD 3233/4885 |
| US-20180243239-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | CCNY, STS, ARSA | CYP1A2 606/4885MAPT 4501/4885HPGD 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.