Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 7/20 | 0.48 |
| ▸ | NOS2 | P35228 | 7/20 | 0.48 |
| ▸ | NOS3 | P29474 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29157454 | 0.98 | ENPP2 (0.58) | ENPP2LOXL2PNMTNOS1NOS2 | |
| Phenol SCHEMBL1458667 | 0.86 | ENPP2 (0.62) | ENPP2LOXL2PNMTNOS1NOS2 | |
| Phosphoric Acid SCHEMBL29187233 | 0.86 | ENPP2 (0.47) | ENPP2LOXL2PNMTNOS1NOS2 | |
| Benzylamine SCHEMBL8108778 | 0.86 | LOXL2 (0.70) | ENPP2LOXL2ANPEPERAP1CYP1A2 | |
| Benzylamine SCHEMBL7933802 | 0.86 | LOXL2 (0.70) | ENPP2LOXL2ANPEPERAP1CYP1A2 | |
| Benzylamine SCHEMBL28106183 | 0.86 | LOXL2 (0.70) | ENPP2LOXL2ANPEPERAP1CYP1A2 | |
| Phosphoric Acid SCHEMBL10628319 | 0.85 | ENPP2 (0.50) | ENPP2LOXL2PNMTNOS1NOS2 | |
| Ammonia Solution, Strong SCHEMBL6899866 | 0.85 | LOXL2 (0.67) | ENPP2LOXL2PNMTNOS1NOS2 | |
| SCHEMBL36008 | 0.83 | LOXL2 (0.71) | ENPP2LOXL2PNMTNOS1NOS2 | |
| SCHEMBL10422276 | 0.83 | LOXL2 (0.71) | ENPP2LOXL2PNMTNOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586302-A | Synthetic method and application of flame retardant with active ammonium phosphate group | 南京工业大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117586302-A | Synthetic method and application of flame retardant with active ammonium phosphate group | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586302-A | Synthetic method and application of flame retardant with active ammonium phosphate group | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |