Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610556 | 0.87 | FAAH (0.44) | HTR2ASMN1; SMN2CES1FAAHL3MBTL1 | |
| SCHEMBL6567776 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL144711 | 0.76 | MAOB (0.52) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL8068020 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL3973128 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL7405977 | 0.72 | GPR52 (0.41) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL9715286 | 0.72 | GPR52 (0.57) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL7762166 | 0.72 | GPR52 (0.57) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL205556 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL7762164 | 0.72 | GPR52 (0.57) | ALDH1A1HPGDALOX15ALOX12CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856275-B2 | Synthesis and use of fluorinated compounds | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-01-02 | — | — | US | disclosed |
| WO-2014126990-A1 | SYNTHESIS AND USE OF FLUORINATED COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-08-21 | — | — | WO | disclosed |
| EP-2225227-A2 | COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009065920-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| CN-1239957-A | Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| EP-0381149-B1 | Optically active compound, liquid crystal composition and liquid crystal device comprising same | SHARP KK (JP) | 1996-03-27 | — | — | EP | disclosed |