Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039857 | 0.77 | KDM4E (0.48) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL8160950 | 0.73 | KDM4E (0.54) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL8153468 | 0.73 | — | — | |
| SCHEMBL617390 | 0.72 | KDM4E (0.73) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL29096270 | 0.70 | KDM4E (0.70) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL29096269 | 0.70 | KDM4E (0.70) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL18413430 | 0.70 | GAA (0.38) | KDM4EGAACYP1A2HIF1AALDH1A1 | |
| SCHEMBL7921596 | 0.70 | KDM4E (0.55) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL10343508 | 0.69 | KDM4E (0.40) | KDM4EGAACYP1A2LMNAPOLB | |
| SCHEMBL1400875 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| EP-2221289-B1 | METHOD OF PRODUCING ALCOHOL | MITSUBISHI CHEM CORP (JP) | 2016-10-26 | — | — | EP | disclosed |
| US-8318990-B2 | Process of producing alcohol | MITSUBISHI CHEMICAL CORPORATION (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20100298613-A1 | PROCESS OF PRODUCING ALCOHOL | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| CN-101855189-A | Process for producing alcohol | MITSUBISHI CHEM CORP | 2010-10-06 | — | — | CN | disclosed |
| EP-2221289-A1 | METHOD OF PRODUCING ALCOHOL | Mitsubishi Chemical Corporation (JP) | 2010-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298613-A1 | PROCESS OF PRODUCING ALCOHOL | ADH1C, ADH1A, ADH5 | KDM4E 856/4885GAA 3906/4885CYP1A2 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.