Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190222 | 0.90 | NR3C1 (0.32) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL2537398 | 0.87 | NR3C1 (0.35) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL9950522 | 0.86 | LMNA (0.36) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL30666800 | 0.82 | LMNA (0.38) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL17460403 | 0.82 | LMNA (0.38) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL4753902 | 0.82 | ALOX15 (0.38) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL2337806 | 0.82 | ALDH1A1 (0.38) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL10646190 | 0.82 | ALDH1A1 (0.38) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL1972754 | 0.81 | NR3C1 (0.39) | NR3C1NR3C2PGRLMNAALDH1A1 | |
| SCHEMBL1941890 | 0.81 | LMNA (0.37) | NR3C1NR3C2PGRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083272-A | 4-alkoxy-6-oxo-pyridazine derivatives that modulate NLRP3 | 詹森药业有限公司 | 2023-11-17 | — | — | CN | disclosed |