Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13538968 | 0.79 | MEN1 (0.32) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL25164045 | 0.78 | RXRA (0.40) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL26654252 | 0.77 | DGAT1 (0.41) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL28012488 | 0.77 | L3MBTL1 (0.51) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL27932212 | 0.75 | L3MBTL1 (0.50) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL25096494 | 0.74 | MEN1 (0.38) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL13672446 | 0.74 | MAPT (0.57) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL28395431 | 0.74 | MEN1 (0.40) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL747149 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2ALMNAL3MBTL1TDP1 | |
| SCHEMBL17253107 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2ALMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597339-A | Aryl 3-oxo-piperazine carboxamides and heteroaryl 3-oxo-piperazine carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2024-02-23 | — | — | CN | disclosed |