Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505120 | 0.89 | HRH3 (0.51) | HRH3HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL24928106 | 0.80 | FAP (0.73) | FAP | |
| SCHEMBL29362282 | 0.79 | HTR1A (0.65) | HRH3HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1520512 | 0.79 | HTR1A (0.65) | HRH3HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28069310 | 0.77 | HTR1A (0.63) | HRH3HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28462567 | 0.77 | PREP (0.72) | FAP | |
| SCHEMBL6984768 | 0.75 | HTR1A (0.59) | HRH3HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11566047 | 0.73 | CCKBR (0.49) | HRH3ADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL21101629 | 0.73 | PREP (0.64) | FAP | |
| SCHEMBL19563520 | 0.73 | HRH3 (1.00) | HRH3HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642188-A | Radiopharmaceuticals based on ((R) -1- ((6-hydrazinonicotinyl) -D-alanyl) pyrrolidin-2-yl) boronic acid (HYNIC-IFAP) for detection of fibroblast activation protein overexpression | 国家核研究所 | 2024-03-01 | — | — | CN | disclosed |