Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G6 | O60733 | 2/20 | 0.60 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.60 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.52 |
| ▸ | LYPLA1 | O75608 | 3/20 | 0.51 |
| ▸ | LYPLA2 | O95372 | 3/20 | 0.51 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.51 |
| ▸ | PNLIP | P16233 | 3/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448340 | 1.00 | PLA2G6 (0.60) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 | |
| SCHEMBL2916300 | 1.00 | PLA2G6 (0.60) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 | |
| SCHEMBL2916334 | 0.87 | FASN (0.61) | PLA2G6PLA2G4ADAGLAFASNNAAA | |
| SCHEMBL2916335 | 0.87 | FASN (0.61) | PLA2G6PLA2G4ADAGLAFASNNAAA | |
| SCHEMBL2916331 | 0.87 | FASN (0.61) | PLA2G6PLA2G4ADAGLAFASNNAAA | |
| SCHEMBL19514903 | 0.83 | PLA2G6 (0.84) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 | |
| SCHEMBL19514898 | 0.83 | PLA2G6 (0.84) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 | |
| SCHEMBL19514935 | 0.83 | PLA2G6 (0.84) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 | |
| SCHEMBL19514905 | 0.83 | PLA2G6 (0.84) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 | |
| SCHEMBL17979630 | 0.83 | PLA2G6 (0.80) | PLA2G6PLA2G4ADAGLALYPLA1LYPLA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197386-A1 | Alkyl carbamate-substituted beta-lactones, process and intermediate products for their preparation, and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-09-08 | — | — | US | claimed |
| EP-1751126-B1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | ABBOTT PRODUCTS GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1751126-A1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | Solvay Pharmaceuticals GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| US-7074822-B2 | Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20050197386-A1 | Alkyl carbamate-substituted beta-lactones, process and intermediate products for their preparation, and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-09-08 | — | — | US | disclosed |
| WO-2005080366-A1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197386-A1 | Alkyl carbamate-substituted beta-lactones, process and intermediate products for their preparation, and pharmaceutical compositions containing them | PNLIP, CEL, LIPE | PLA2G6 193/4885PLA2G4A 198/4885DAGLA 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.