Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019452 | 1.00 | NOTUM (0.44) | NOTUMOPRM1OPRK1OPRL1PRCP | |
| SCHEMBL14170126 | 0.72 | ADRA2A (0.42) | OPRM1OPRK1OPRL1HTR2AHTR2C | |
| SCHEMBL15468333 | 0.72 | HTR2A (0.40) | NOTUMOPRM1OPRK1OPRL1PRCP | |
| SCHEMBL14169952 | 0.71 | PDPK1 (0.47) | NOTUMOPRM1OPRK1OPRL1MGLL | |
| SCHEMBL30124965 | 0.70 | SRD5A1 (0.42) | NOTUMOPRM1OPRK1OPRL1PRCP | |
| SCHEMBL14169932 | 0.69 | ADRA2A (0.43) | PRCPHTR2AHTR2CHTR2B | |
| SCHEMBL30125068 | 0.68 | NOTUM (0.38) | NOTUMSRD5A1 | |
| SCHEMBL30124862 | 0.68 | NOTUM (0.38) | NOTUMSRD5A1 | |
| SCHEMBL4521091 | 0.68 | ALDH1A1 (0.41) | OPRM1OPRK1OPRL1 | |
| SCHEMBL4521089 | 0.68 | ALDH1A1 (0.41) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412975-A | Heterocyclic compounds and their use | 伊科诺姆有限公司 | 2024-01-16 | — | — | CN | disclosed |