SCHEMBL30124965

SCHEMBL30124965

CC1Cc2ccccc2C2CCC(=O)N12

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 2/20 0.42
CHRNA7 P36544 1/20 0.41
PRCP P42785 1/20 0.40
NOTUM Q6P988 1/20 0.40
OPRM1 P35372 4/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
OPRK1 P41145 1/20 0.38
OPRL1 P41146 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15468300 0.78 OPRM1 (0.43) CHRNA7OPRM1TRPM8
SCHEMBL11726212 0.78 TAAR1 (0.41) PRCPOPRM1
SCHEMBL11729232 0.78 TAAR1 (0.41) PRCPOPRM1
SCHEMBL15468333 0.71 HTR2A (0.40) SRD5A1PRCPNOTUMOPRM1OPRK1
SCHEMBL12747426 0.70 ACE (0.50)
SCHEMBL29165282 0.70 NOTUM (0.44) SRD5A1PRCPNOTUMOPRM1OPRK1
SCHEMBL14170111 0.70 BRD4 (0.38) PRCPNOTUMOPRM1
SCHEMBL31019452 0.70 NOTUM (0.44) SRD5A1PRCPNOTUMOPRM1OPRK1
SCHEMBL29961061 0.69 ALDH1A1 (0.56) SRD5A1CHRNA7OPRM1TRPM8OPRK1
Iodide SCHEMBL7009470 0.68 OPRM1 (0.53) CHRNA7PRCPOPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313985-A2 HETEROCYCLIC COMPOUNDS AND THEIR USE Equinorm Ltd (FI) 2024-02-07 EP claimed
WO-2022207979-A2 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE EQUINORM LTD (FI) 2022-10-06 WO claimed