Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.64 |
| ▸ | IL6 | P05231 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.64 |
| ▸ | GLUL | P15104 | 1/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prednisolone Metazoate SCHEMBL5483006 | 0.99 | PGR (0.69) | PGRHIF1ALMNANR3C1HSD17B10 | |
| Prednisolone Metazoate SCHEMBL29379658 | 0.93 | PGR (0.68) | PGRHIF1ALMNANR3C1HSD17B10 | |
| Prednisolone Metazoate SCHEMBL5013651 | 0.93 | PGR (0.68) | PGRHIF1ALMNANR3C1HSD17B10 | |
| Prednisolone Metazoate SCHEMBL1042225 | 0.93 | PGR (0.68) | PGRHIF1ALMNANR3C1HSD17B10 | |
| Prednisolone Metazoate SCHEMBL2796992 | 0.93 | PGR (0.68) | PGRHIF1ALMNANR3C1HSD17B10 | |
| Prednisolone Metazoate SCHEMBL5483013 | 0.93 | PGR (0.68) | PGRHIF1ALMNANR3C1HSD17B10 | |
| SCHEMBL28852123 | 0.89 | HIF1A (0.73) | PGRHIF1ALMNANR3C1HSD17B10 | |
| SCHEMBL27462874 | 0.88 | HIF1A (0.72) | PGRHIF1ALMNANR3C1HSD17B10 | |
| SCHEMBL9836047 | 0.88 | PGR (0.71) | PGRHIF1ALMNANR3C1HSD17B10 | |
| Prednisolone SCHEMBL4318103 | 0.87 | NR3C1 (0.71) | PGRHIF1ALMNANR3C1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130230588-A1 | CONTROLLED RELEASE COMPOSITIONS | TEMREL LIMITED (GB) | 2013-09-05 | — | — | US | disclosed |
| EP-1519717-B1 | CONTROLLED RELEASE COMPOSITION | TEMREL LTD (VG) | 2010-09-29 | — | — | EP | disclosed |
| US-20060127484-A1 | Controlled release composition | TEMREL LIMITED (VG) | 2006-06-15 | — | — | US | disclosed |
| EP-0772443-B1 | PREDNISOLONE METASULPHOBENZOATE PREPARATION FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | ENTEROTECH LIMITED (GB) | 2000-12-06 | — | — | EP | disclosed |