SCHEMBL2916586

SCHEMBL2916586

COc1cc(CCCO)cc(-c2ccccc2)c1O

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 3/20 0.79
ALOX5 P09917 5/20 0.54
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
BACE1 P56817 1/20 0.44
AKR1B1 P15121 1/20 0.44
TNKS O95271 1/20 0.43
LTA4H P09960 1/20 0.43
PDE4B Q07343 1/20 0.43
HK2 P52789 1/20 0.42
PDE4D Q08499 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914750 0.84 TNKS2 (0.51) TNKS2ALOX5BACE1LTA4HPDE4B
SCHEMBL2914283 0.82 TNKS2 (0.86) TNKS2ALOX5KDM4EGAAMAPT
SCHEMBL2914798 0.81 TNKS2 (0.63) TNKS2ALOX5KDM4EGAAMAPT
SCHEMBL2916168 0.80 TNKS2 (0.49) TNKS2GAABACE1LTA4HPDE4B
SCHEMBL510185 0.77 BACE1 (0.54) GAABACE1PDE4BHK2PDE4D
SCHEMBL10931154 0.77 PTPN1 (0.51) TNKS2ALOX5BACE1PDE4B
SCHEMBL9178161 0.77 PTPN1 (0.51) TNKS2ALOX5BACE1PDE4B
SCHEMBL2910937 0.77 GAA (0.47) TNKS2KDM4EGAAMAPTBACE1
SCHEMBL18906736 0.76 TNKS2 (0.75) TNKS2ALOX5KDM4EAKR1B1TNKS
SCHEMBL9182437 0.76 PTPN1 (0.50) TNKS2ALOX5MAPTBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 TNKS2 3493/4885ALOX5 418/4885KDM4E 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.