SCHEMBL29167102

SCHEMBL29167102

CCCc1ccc(C#Cc2ccc(B(O)O)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPL P06858 6/20 0.78
LIPG Q9Y5X9 6/20 0.78
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
TRPV1 Q8NER1 1/20 0.58
MGLL Q99685 1/20 0.58
ACACB O00763 5/20 0.48
ENPP2 Q13822 1/20 0.44
F11 P03951 1/20 0.42
FFAR1 O14842 2/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257735 0.88 LPL (1.00) LPLLIPGCA1CA2TRPV1
SCHEMBL8141107 0.84 ACACB (0.54) LPLLIPGCA2ACACBFFAR1
SCHEMBL9328434 0.84 ACACB (0.54) LPLLIPGCA2ACACBFFAR1
SCHEMBL257620 0.82 LPL (0.88) LPLLIPGCA1CA2TRPV1
SCHEMBL9511319 0.82 ACACB (0.53) LPLLIPGCA2ACACBFFAR1
SCHEMBL806833 0.79 ENPP2 (0.64) LPLLIPGCA1CA2MGLL
SCHEMBL806832 0.79 ENPP2 (0.64) LPLLIPGCA1CA2MGLL
SCHEMBL7474712 0.79 LPL (0.81) LPLLIPGCA1CA2TRPV1
SCHEMBL4054994 0.79 ESR1 (0.53) LPLLIPGCA2ACACBFFAR1
SCHEMBL9328206 0.78 CYP2A6 (0.52) LPLLIPGCA2ACACBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117623987-A Isothiocyanate liquid crystal compound containing 2, 5-difluoro substituted benzene and synthesis method 西安近代化学研究所 2024-03-01 CN disclosed