SCHEMBL257620

SCHEMBL257620

CCCc1ccc(-c2ccc(B(O)O)cc2)cc1

nearest known ligand 0.88

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.88
LIPG Q9Y5X9 7/20 0.88
CA2 P00918 3/20 0.68
CA1 P00915 2/20 0.68
TRPV1 Q8NER1 3/20 0.63
MGLL Q99685 2/20 0.63
F11 P03951 1/20 0.47
MCL1 Q07820 1/20 0.45
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
ALOX5 P09917 1/20 0.42
RARB P10826 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257735 0.94 LPL (1.00) LPLLIPGCA2CA1TRPV1
SCHEMBL13454827 0.88 CA1 (0.89) LPLLIPGCA2CA1TRPV1
SCHEMBL1791067 0.86 LPL (0.89) LPLLIPGCA2CA1TRPV1
Methyl Alcohol SCHEMBL28643312 0.85 LPL (0.86) LPLLIPGCA2CA1TRPV1
SCHEMBL15087090 0.85 LPL (0.89) LPLLIPGCA2CA1TRPV1
SCHEMBL7111292 0.85 LPL (0.89) LPLLIPGCA2CA1TRPV1
SCHEMBL7474712 0.84 LPL (0.81) LPLLIPGCA2CA1TRPV1
SCHEMBL2482085 0.83 LPL (0.86) LPLLIPGCA2CA1TRPV1
SCHEMBL29167102 0.82 LPL (0.78) LPLLIPGCA2CA1TRPV1
SCHEMBL4802707 0.82 LPL (0.54) LPLLIPGCA2MGLLMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112470045-B Optical filter and display device 住友化学株式会社 2023-08-08 CN disclosed
CN-111051473-B Liquid crystal composition and liquid crystal display element 捷恩智株式会社 2023-08-01 CN disclosed
CN-111148769-B Liquid crystal composition, phase difference film and method for producing same, transfer laminate, optical member and method for producing same, and display device 大日本印刷株式会社 2023-01-10 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20190284475-A1 LIQUID CRYSTAL COMPOUND AND A LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME DAXIN MATERIALS CORP. (TW) 2019-09-19 US disclosed
US-10221114-B2 Liquid crystal compound having tetrafluoro cyclohexadiene structure showing negative anisotropy, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2019-03-05 US disclosed
CN-105838385-B Liquid crystal compound, liquid crystal composition containing same, electro-optical display and liquid crystal display device 达兴材料股份有限公司 2019-01-29 CN disclosed
US-10113116-B2 Liquid crystal compound and liquid crystal composition employing the same DAXIN MATERIALS CORPORATION (TW) 2018-10-30 US disclosed
US-20180094191-A1 LIQUID CRYSTAL COMPOUND CONTAINING 2,3,4-TRISUBSTITUTED BENZENE AND COMPOSITION THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD (CN) 2018-04-05 US disclosed
US-9822301-B2 Alkenyl ether compound and a liquid crystal composition using the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY DISCOVERY, INC. (US) 2009-04-16 US disclosed
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY DISCOVERY, INC. (US) 2009-04-16 US disclosed
WO-2008063300-A2 BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2008-05-29 WO disclosed
EP-1644460-B1 SUBSTITUTED ANTHRACENES MERCK PATENT GMBH (DE) 2008-01-30 EP disclosed
US-20070014934-A1 Substituted anthracenes MERCK PATENT GMBH (DE) 2007-01-18 US disclosed
EP-1223209-B1 Fluorinated fluorenes and use thereof in liquid crystal mixtures CLARIANT INT LTD (CH) 2004-03-03 EP disclosed
EP-1223209-A1 Fluorinated fluorenes and use thereof in liquid crystal mixtures CLARIANT INTERNATIONAL LTD. (CH) 2002-07-17 EP disclosed
US-5637257-A LIQUID CRYSTAL DISPLAYING MERCK PATENT GESELLSCHAFT MLT BESCHRANKTER HAFTUNG (DE) 1997-06-10 US disclosed
US-5482653-A FOR LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-01-09 US disclosed
EP-0428666-B1 FLUORO-CHLORO-BENZENE DERIVATIVES MERCK PATENT GMBH (DE) 1995-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10113116-B2 Liquid crystal compound and liquid crystal composition employing the same ZYX, MLX, NPM1 LPL 993/4885LIPG 2470/4885CA2 2293/4885
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 LPL 180/4885LIPG 272/4885CA2 1331/4885
US-10221114-B2 Liquid crystal compound having tetrafluoro cyclohexadiene structure showing negative anisotropy, liquid crystal composition, and liquid crystal display device OCIAD2, CNOT1, OCIAD1 LPL 3538/4885LIPG 3807/4885CA2 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.