SCHEMBL29167682

SCHEMBL29167682

CC(C)(C)[Si](C)(C)Oc1[c]cc(F)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.35
FEN1 P39748 2/20 0.35
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA9 Q16790 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29026302 0.80 CA12 (0.31) ALOX5APFEN1CA12CA1CA9
SCHEMBL3970679 0.75 ALDH1A1 (0.31)
SCHEMBL29167690 0.74 ALOX5AP (0.37) ALOX5APFEN1CA12CA1CA9
SCHEMBL29167700 0.73 DRD2 (0.30)
SCHEMBL29026260 0.72 LTA4H (0.38) CA12CA1CA9
SCHEMBL5468624 0.71 TRPA1 (0.38)
SCHEMBL5468620 0.71 TRPA1 (0.38)
SCHEMBL2548669 0.71 PREP (0.46) ALOX5APFEN1CA12CA1CA9
SCHEMBL203111 0.70 CA12 (0.32) ALOX5APFEN1CA12CA1CA9
SCHEMBL161096 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624029-A Arylpyridine or arylpiperidine derivative or salt thereof, synthesis and application and medicine 赣江中药创新中心 2024-03-01 CN disclosed