Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31211291 | 0.87 | PARP1 (0.44) | KDM4EL3MBTL1ATM | |
| SCHEMBL27537632 | 0.78 | MYC (0.46) | KDM4ERAB9AKDM4AEGLN1L3MBTL1 | |
| SCHEMBL27359877 | 0.73 | KDM4E (0.38) | KDM4ERAB9AKDM4AEGLN1L3MBTL1 | |
| SCHEMBL19918850 | 0.70 | MAPT (0.44) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28442586 | 0.70 | LMNA (0.50) | KDM4EL3MBTL1LMNACYP2C9MEN1 | |
| SCHEMBL120218 | 0.70 | ALDH1A1 (0.50) | KDM4ERAB9AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL25192537 | 0.70 | ALDH1A1 (0.49) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1297983 | 0.68 | KDM4E (0.54) | KDM4EHPGD | |
| SCHEMBL24553750 | 0.67 | MEN1 (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL23809440 | 0.67 | POLB (0.36) | L3MBTL1HPGDLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |