Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 9/20 | 0.41 |
| ▸ | AURKA | O14965 | 5/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168339 | 0.87 | KDM4E (0.41) | KDM4EL3MBTL1ATM | |
| SCHEMBL30088599 | 0.73 | PARP1 (0.46) | PARP1KDM4EL3MBTL1RPS6KB1AURKA | |
| SCHEMBL10126200 | 0.68 | KMT2A (0.68) | PARP1KDM4E | |
| SCHEMBL28138780 | 0.67 | PIM3 (0.44) | PARP1KDM4EL3MBTL1 | |
| Ethenzamide SCHEMBL27612766 | 0.66 | MAPT (0.68) | PARP1KDM4EL3MBTL1 | |
| Ethenzamide SCHEMBL25624 | 0.66 | MAPT (0.68) | PARP1KDM4EL3MBTL1 | |
| SCHEMBL7534601 | 0.66 | ALDH1A1 (0.49) | PARP1KDM4E | |
| SCHEMBL30344154 | 0.66 | CYP3A4 (0.50) | L3MBTL1 | |
| SCHEMBL3189724 | 0.66 | TSHR (0.53) | L3MBTL1 | |
| SCHEMBL288797 | 0.66 | TSHR (0.45) | PARP1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182778-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |