SCHEMBL120218

SCHEMBL120218

CCOc1c(C(=O)O)cccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
KDM4E B2RXH2 3/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 2/20 0.49
ABL1 P00519 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
RIN1 Q13671 1/20 0.49
ALOX15 P16050 1/20 0.46
TSHR P16473 2/20 0.46
NOTUM Q6P988 1/20 0.45
HTT P42858 1/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3424538 0.89 MAPK1 (0.53) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL3723435 0.89 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL29768766 0.89 MAPK1 (0.53) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL1003309 0.89 CLCN2 (0.49) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL30597481 0.89 CLCN2 (0.49) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL1989131 0.89 ALDH1A1 (0.62) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL6905551 0.88 LMNA (0.55) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL2673723 0.88 RAB9A (0.45) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL16534370 0.87 MAPT (0.50) ALDH1A1MEN1KMT2AHPGDHSD17B10
SCHEMBL21828877 0.87 HSD17B10 (0.51) ALDH1A1MEN1KMT2AHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020159436-A1 WATER CHANNEL AND METHOD OF FORMING SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-08-06 WO claimed
EP-4729049-A1 SUSTAINED RELEASE DOSAGE FORM FOR LOW SOLUBILITY COMPOUND AXITINIB AND METHODS FOR PREPARING OF THIS SUSTAINED RELEASE DOSAGE FORM Emoviar PharmaCon GmbH (DE) 2026-04-22 EP disclosed
EP-4729052-A1 SUSTAINED RELEASE DOSAGE FORM FOR LOW SOLUBILITY COMPOUND TETRAHYDROCANNABINOL AND METHODS FOR PREPARING OF THIS SUSTAINED RELEASE DOSAGE FORM Emoviar PharmaCon GmbH (DE) 2026-04-22 EP disclosed
US-12599610-B2 Solid dosage formulations of an orexin receptor antagonist MERCK SHARP & DOHME LLC (US) 2026-04-14 US disclosed
EP-3725778-B2 FORMULATIONS OF ENZALUTAMIDE MEDIVATION PROSTATE THERAPEUTICS LLC (US) 2026-01-07 EP disclosed
US-12502357-B2 Formulations of enzalutamide ASTELLAS PHARMA INC. (JP) 2025-12-23 US disclosed
US-12447128-B2 Formulations of enzalutamide ASTELLAS PHARMA INC. (JP) 2025-10-21 US disclosed
US-20250228840-A1 METHODS OF TREATING SJÖGREN-LARSSEN SYNDROME ALDEYRA THERAPEUTICS, INC. 2025-07-17 US disclosed
US-20250221997-A1 TYK2 INHIBITOR FORMULATIONS AND METHODS OF MAKING THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-07-10 US disclosed
US-20250215002-A1 SOLID FORMS OF TYK2 INHIBITORS AND METHODS OF USE NIMBUS LAKSHMI, INC. 2025-07-03 US disclosed
WO-2002011710-A2 PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS PFIZER PRODUCTS INC. (US) 2002-02-14 WO disclosed
US-20020006443-A1 Drug in a solubility-improved form with a concentration-enhancing polymer such as hydroxypropyl methyl cellulose acetate succinate; combination improves bioavailability relative to a control of just solubility improved form BEND RESEARCH, INC. 2002-01-17 US disclosed
US-20010053778-A1 Pharmaceutical compositions of glycogen phosphorylase inhibitors BEND RESEARCH, INC. 2001-12-20 US disclosed
US-20010053791-A1 Glycogen phosphorylase inhibitor BEND RESEARCH, INC. 2001-12-20 US disclosed
WO-2001068092-A2 GLYCOGEN PHOSPHORYLASE INHIBITOR PFIZER PRODUCTS INC. (US) 2001-09-20 WO disclosed
WO-2001047495-A1 PHARMACEUTICAL COMPOSITIONS PROVIDING ENHANCED DRUG CONCENTRATIONS PFIZER PRODUCTS INC. (US) 2001-07-05 WO disclosed
CN-1267753-A Polyurethane elastic silk and elastic braided fabric TOYO BOSEKI (JP) 2000-09-27 CN disclosed
EP-1027886-A2 Pharmaceutical solid dispersions Pfizer Products Inc. (US) 2000-08-16 EP disclosed
US-6080833-A BIS(HYDROXYALKOXYLATED) 1,1'-SPIROBIINDAN POLYCARBONATES AND POLYESTERS POLYMERS AND CURABLE COMPOUNDS SUCH AS BIS(ACRYLATED ALKOXY)SPIROBIINDANS; ALSO POLYAMIDES AND POLYIMIDES CONTAINING SPIROBIINDAN GROUPS MITSUI CHEMICALS, INC. (JP) 2000-06-27 US disclosed
EP-0822545-A2 Optical component and spirobiindan polymer therefor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599610-B2 Solid dosage formulations of an orexin receptor antagonist CRH, HCRTR2, HCRTR1 ALDH1A1 3659/4885MEN1 3111/4885KMT2A 514/4885
US-12502357-B2 Formulations of enzalutamide AR, KLK3, NR5A1 ALDH1A1 1743/4885MEN1 1023/4885KMT2A 578/4885
US-20250215002-A1 SOLID FORMS OF TYK2 INHIBITORS AND METHODS OF USE TYK2, JAK2, SGK2 ALDH1A1 4861/4885MEN1 2348/4885KMT2A 250/4885
US-20250221997-A1 TYK2 INHIBITOR FORMULATIONS AND METHODS OF MAKING THE SAME TYK2, JAK1, JAK2 ALDH1A1 4873/4885MEN1 801/4885KMT2A 166/4885
US-20010053791-A1 Glycogen phosphorylase inhibitor PYGL, PYGM, GYS2 ALDH1A1 2541/4885MEN1 3048/4885KMT2A 3727/4885
US-20010053778-A1 Pharmaceutical compositions of glycogen phosphorylase inhibitors PYGL, PYGM, GYS2 ALDH1A1 3063/4885MEN1 3357/4885KMT2A 3572/4885
US-20250228840-A1 METHODS OF TREATING SJÖGREN-LARSSEN SYNDROME SSB, HRH2, ASAH2 ALDH1A1 1676/4885MEN1 2697/4885KMT2A 2869/4885
US-12447128-B2 Formulations of enzalutamide AR, KLK3, NR5A1 ALDH1A1 1743/4885MEN1 1023/4885KMT2A 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.