Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075113 | 0.81 | ALDH1A1 (0.53) | HDAC6HDAC8NAMPTALDH1A1 | |
| SCHEMBL28205358 | 0.78 | NAMPT (0.49) | HDAC6HDAC8DPP9NAMPTALDH1A1 | |
| SCHEMBL1027717 | 0.77 | NAMPT (0.54) | HDAC6HDAC8NAMPTALDH1A1 | |
| SCHEMBL11816169 | 0.76 | HDAC6 (0.45) | HDAC6HDAC8HDAC1ALDH1A1 | |
| SCHEMBL28956614 | 0.75 | HDAC6 (0.50) | HDAC6HDAC8HDAC1NAMPT | |
| SCHEMBL2814463 | 0.75 | KMT2A (0.57) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11828577 | 0.75 | HDAC6 (0.44) | HDAC6HDAC8HDAC1ALDH1A1 | |
| SCHEMBL8205780 | 0.74 | DPP7 (0.47) | HDAC6HDAC8HSP90AA1HSP90AB1DPP4 | |
| SCHEMBL14048143 | 0.74 | DPP8 (0.54) | HSP90AA1DPP4DPP8DPP9DPP7 | |
| SCHEMBL14817233 | 0.74 | ALDH1A1 (0.63) | HDAC6HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |