SCHEMBL29168804

SCHEMBL29168804

COC1(OC)C=CC=CC1NS(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.46
CA1 P00915 3/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3378076 0.72 ALDH1A1 (0.40) CA2CA1CA12CA9CA3
SCHEMBL19999277 0.67 CA2 (0.65) CA2CA1CA12CA9CA3
SCHEMBL29168802 0.67 CA2 (0.44) CA2CA1CA12CA9CA3
SCHEMBL9815588 0.66 CA2 (0.59) CA2CA1CA12CA9CA3
SCHEMBL28045965 0.66 KDM4E (0.61) CA2CA1CA12CA9CA3
SCHEMBL526906 0.65 CA2 (1.00) CA2CA1CA12CA9CA3
SCHEMBL10494215 0.64 CA2 (0.70) CA2CA1CA12CA9CA3
SCHEMBL20271516 0.64 SMN1; SMN2 (0.73) CA2CA1CA12CA9CA3
SCHEMBL6534890 0.64 CA2 (0.59) CA2CA1CA12CA9CA3
SCHEMBL5723140 0.64 SMN1; SMN2 (0.68) CA2CA1CA12CA9CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430544-A Method for preparing isoindoline compound by taking alpha-amino acetal as substrate 南京工业大学 2024-01-23 CN claimed