Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | CA3 | P07451 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999277 | 0.81 | CA2 (0.65) | CA2CA1CA12CA9CA14 | |
| SCHEMBL3046201 | 0.77 | CA2 (0.65) | CA2CA1CA12CA9CA14 | |
| SCHEMBL27956824 | 0.77 | CA2 (0.59) | CA2CA1CA12CA9CA14 | |
| SCHEMBL1242008 | 0.75 | ALOX5 (0.56) | CA2CA1CA12CA9CA14 | |
| SCHEMBL16310093 | 0.75 | KMT2A (0.56) | CA2CA1CA12CA9CA14 | |
| SCHEMBL25619820 | 0.75 | CA2 (0.61) | CA2CA1CA12CA9CA14 | |
| SCHEMBL29039629 | 0.75 | ADAMTS4 (0.47) | CA2CA1CA12CA9CA14 | |
| SCHEMBL5018973 | 0.74 | CA2 (0.55) | CA2CA1CA12CA9CA14 | |
| SCHEMBL526906 | 0.74 | CA2 (1.00) | CA2CA1CA12CA9CA14 | |
| SCHEMBL14627755 | 0.74 | CA1 (0.59) | CA2CA1MMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | disclosed |