Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | ELOC | Q15369 | 1/20 | 0.33 |
| ▸ | ELOB | Q15370 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295159 | 0.78 | TAAR1 (0.37) | — | |
| SCHEMBL7168345 | 0.78 | TSHR (0.37) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL4933345 | 0.77 | CALM1 (0.38) | TSHRPRSS1PRSS2PRSS3HPGD | |
| SCHEMBL29037444 | 0.76 | ALDH1A1 (0.47) | TSHRPTGS1CA12CA1CA2 | |
| SCHEMBL9672376 | 0.74 | IDO1 (0.45) | TSHRLTA4HCA12CA1CA2 | |
| SCHEMBL11444843 | 0.74 | ALDH1A1 (0.48) | TSHRCHKA | |
| Fluoride SCHEMBL28282617 | 0.72 | TSHR (0.62) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL2246496 | 0.71 | LOXL2 (0.48) | TSHR | |
| SCHEMBL41775 | 0.69 | TSHR (0.67) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL15233235 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480008-A | Electro-grafted membranes for DNA synthesis | 金斯瑞美国有限公司 | 2024-01-30 | — | — | CN | disclosed |