SCHEMBL7168345

SCHEMBL7168345

F[B-](F)(F)F.N#[N+]c1ccc(CO)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
VHL P40337 1/20 0.33
ELOC Q15369 1/20 0.33
ELOB Q15370 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33
MKNK2 Q9HBH9 1/20 0.33
LTA4H P09960 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5376086 0.91 TSHR (0.43) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL1792657 0.83 CA2 (0.45) TSHRCA12CA1CA2CA4
SCHEMBL6870559 0.82 ALDH1A1 (0.38) TSHR
SCHEMBL5370217 0.81
SCHEMBL5380526 0.81
SCHEMBL23356017 0.78 LOXL2 (0.44) CA12CA1CA2CA4CA6
SCHEMBL5369605 0.78 CA1 (0.33) CA1CA2
SCHEMBL29169705 0.78 TSHR (0.37) TSHRPRSS1PRSS2PRSS3VHL
SCHEMBL2232785 0.77
Ammonia Solution, Strong SCHEMBL27826486 0.77 CYP2A6 (0.39) TSHRCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240279828-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS Nanjing GenScript Biotech Co., Ltd. (CN) 2024-08-22 US claimed
EP-4347110-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS Genscript USA Inc. (US) 2024-04-10 EP claimed
CN-117480008-A Electro-grafted membranes for DNA synthesis 金斯瑞美国有限公司 2024-01-30 CN claimed
WO-2022256303-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS GENSCRIPT USA INC. (US) 2022-12-08 WO claimed
US-20240279828-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS Nanjing GenScript Biotech Co., Ltd. (CN) 2024-08-22 US disclosed
EP-4347110-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS Genscript USA Inc. (US) 2024-04-10 EP disclosed
CN-117480008-A Electro-grafted membranes for DNA synthesis 金斯瑞美国有限公司 2024-01-30 CN disclosed
WO-2022256303-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS GENSCRIPT USA INC. (US) 2022-12-08 WO disclosed
EP-1276726-A2 SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS Abbott Laboratories (US) 2003-01-22 EP disclosed
US-20020019527-A1 Substituted phenyl farnesyltransferase inhibitors ABBOTT LABORATORIES 2002-02-14 US disclosed
WO-2001081316-A2 SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS ABBOTT LABORATORIES (US) 2001-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279828-A1 ELECTROGRAFTED FILMS FOR DNA SYNTHESIS DNMT3A, DNMT1, DNMT3B TSHR 2333/4885PRSS1 2891/4885PRSS2 2886/4885
US-20020019527-A1 Substituted phenyl farnesyltransferase inhibitors FNTA, FNTB, SLC10A1 TSHR 3465/4885PRSS1 261/4885PRSS2 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.