Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 4/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.34 |
| ▸ | NOS2 | P35228 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033945 | 0.90 | ALPL (0.38) | KDM4EMAPTGAAALPLMEN1 | |
| SCHEMBL27033421 | 0.82 | MAPT (0.46) | ADRA1DHPGDNPSR1KDM4EMAPT | |
| SCHEMBL29958664 | 0.82 | MAPT (0.46) | ADRA1DHPGDNPSR1KDM4EMAPT | |
| SCHEMBL3834764 | 0.79 | EGFR (0.43) | KDM4EMAPTGAAALPL | |
| SCHEMBL29958529 | 0.76 | KEAP1 (0.40) | KDM4EMAPTCYP2C9ALPLALDH1A1 | |
| SCHEMBL27033835 | 0.76 | KEAP1 (0.40) | KDM4EMAPTCYP2C9ALPLALDH1A1 | |
| SCHEMBL6816520 | 0.74 | PRMT5 (0.36) | HPGDKDM4EMAPTGAATDP1 | |
| SCHEMBL29174287 | 0.74 | MEN1 (0.33) | HPGDKDM4EMAPTGAATDP1 | |
| SCHEMBL28068640 | 0.72 | HPGD (0.45) | HPGDNPSR1KDM4EMAPTCYP1A2 | |
| SCHEMBL1307875 | 0.70 | GAA (0.53) | KDM4EMAPTCYP1A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |